Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
SIRT6
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
sirtuin(silent mating type information regulation 2 homolog) 6
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
NAD-dependent protein deacylase sirtuin-6|NAD-dependent protein deacetylase sirtuin-6|Protein mono-ADP-ribosyltransferase sirtuin-6|Regulatory protein SIR2 homolog 6 (hSIRT6)|SIR2-like protein 6|SIRT6|SIR2L6
Host
Rabbit
UniProt ID
Q8N6T7
Gene ID
23408
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
49kd
Background
NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and