Información del producto
SESN1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
SESN1
Research Area
Cardiovascular
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
sestrin 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Sestrin-1|p53-regulated protein PA26|SESN1|PA26|SEST1
Host
Rabbit
UniProt ID
Q9Y6P5
Gene ID
27244
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
66-68 kDa
Background
Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its i