Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
RSPO3
Research Area
Neuroscience
Form
liquid
Recomended Dilution
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
R-spondin 3 homolog
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
R-spondin-3|Protein with TSP type-1 repeat (hPWTSR)|Roof plate-specific spondin-3 (hRspo3)|Thrombospondin type-1 domain-containing protein 2|RSPO3|PWTSR|THSD2
Host
Rabbit
UniProt ID
Q9BXY4
Gene ID
84870
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
40 kDa
Background
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that a