Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Target
RNF168
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
ring finger protein 168
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase RNF168 (hRNF168)|RING finger protein 168|RING-type E3 ubiquitin transferase RNF168|RNF168
Host
Rabbit
UniProt ID
Q8IYW5
Gene ID
165918
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
65-70 kDa
Background
E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks(DSBs) by binding to ubiqu