Información del producto
PALB2 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
PALB2
Research Area
cancer
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
partner and localizer of BRCA2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Partner and localizer of BRCA2|PALB2|FANCN
Host
Rabbit
UniProt ID
Q86YC2
Gene ID
79728
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
131kd
Background
Plays a critical role in homologous recombination repair(HRR) through its ability to recruit BRCA2 and RAD51 to DNA breaks. Strongly stimulates the DNA strand-invasion activity of RAD51, stabilizes the nucleoprotein filament against a disruptive BRC3-BRC4