Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
NLRP2
Research Area
Immunology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
NLR family, pyrin domain containing 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
NACHT, LRR and PYD domains-containing protein 2|Nucleotide-binding site protein 1|PYRIN domain and NACHT domain-containing protein 1|PYRIN-containing APAF1-like protein 2|NLRP2|NALP2|NBS1|PAN1|PYPAF2
Host
Rabbit
UniProt ID
Q9NX02
Gene ID
55655
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
105-110 kDa
Background
Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a compo