Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP, IHC
Target
NGEF
Research Area
Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
neuronal guanine nucleotide exchange factor
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Ephexin-1|Eph-interacting exchange protein|Neuronal guanine nucleotide exchange factor|NGEF
Host
Rabbit
UniProt ID
Q8N5V2
Gene ID
25791
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
75 kDa
Background
Acts as a guanine nucleotide exchange factor(GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin th