Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
MUC20
Research Area
Cancer, Immunology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
mucin 20, cell surface associated
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Mucin-20 (MUC-20)|MUC20|KIAA1359
Host
Rabbit
UniProt ID
Q8N307
Gene ID
200958
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
70-75kd
Background
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor(HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.