Información del producto
MSH6 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
MSH6
Research Area
Epigenetics, Metabolism, Cancer, Immunology, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
monoclonal
Immunogen
mutS homolog 6
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
DNA mismatch repair protein Msh6 (hMSH6)|G/T mismatch-binding protein (GTBP, GTMBP)|MutS protein homolog 6|MutS-alpha 160 kDa subunit (p160)|MSH6|GTBP
Host
Mouse
UniProt ID
P52701
Gene ID
2956
Purification
Protein A+G purification
Clone Number
4C4
Iso type
IgG2a
Reactivity
Human
Observed MW
160 kDa
Background
Component of the post-replicative DNA mismatch repair system(MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pair