FT-FNab05217
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB |
Target | MLKL |
Research Area | Metabolism |
Form | liquid |
Recomended Dilution | WB: 1:500-1:2000 |
Type Clonality | polyclonal |
Immunogen | mixed lineage kinase domain-like |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | Mixed lineage kinase domain-like protein (hMLKL)|MLKL |
Host | Rabbit |
UniProt ID | Q8NB16 |
Gene ID | 197259 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human |
Observed MW | 54 kDa |
Background | Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characteri |