Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
HSD11B2
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
hydroxysteroid(11-beta) dehydrogenase 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
11-beta-hydroxysteroid dehydrogenase type 2 (11-DH2, 11-beta-HSD2)|11-beta-hydroxysteroid dehydrogenase type II (11-HSD type II, 11-beta-HSD type II)|Corticosteroid 11-beta-dehydrogenase isozyme 2|NAD-dependent 11-beta-hydroxysteroid dehydrogenase|Short c
Host
Rabbit
UniProt ID
P80365
Gene ID
3291
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
40-43 kDa
Background
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.