Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Target
FRS3
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
fibroblast growth factor receptor substrate 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Fibroblast growth factor receptor substrate 3 (FGFR substrate 3)|FGFR-signaling adaptor SNT2|Suc1-associated neurotrophic factor target 2 (SNT-2)|FRS3
Host
Rabbit
UniProt ID
O43559
Gene ID
10817
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
54 kDa
Background
Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.