FT-FNab02384
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB, IHC, IP |
Target | DIABLO |
Research Area | Cancer |
Form | liquid |
Recomended Dilution | WB: 1:500-1:2000 |
Type Clonality | polyclonal |
Immunogen | diablo homolog(Drosophila) |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | Diablo IAP-binding mitochondrial protein|Diablo homolog, mitochondrial|Direct IAP-binding protein with low pI|Second mitochondria-derived activator of caspase (Smac)|Diablo IAP-binding mitochondrial protein, cleaved form|DIABLO|SMAC |
Host | Rabbit |
UniProt ID | Q9NR28 |
Gene ID | 56616 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse, Rat |
Observed MW | 20 kDa |
Background | Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins(IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 |