Información del producto
DIABLO antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
DIABLO
Research Area
Cancer
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
diablo homolog(Drosophila)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Diablo IAP-binding mitochondrial protein|Diablo homolog, mitochondrial|Direct IAP-binding protein with low pI|Second mitochondria-derived activator of caspase (Smac)|Diablo IAP-binding mitochondrial protein, cleaved form|DIABLO|SMAC
Host
Rabbit
UniProt ID
Q9NR28
Gene ID
56616
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
20 kDa
Background
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins(IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3