Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IHC
Target
CARD11
Research Area
Immunology, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
caspase recruitment domain family, member 11
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Caspase recruitment domain-containing protein 11|CARD-containing MAGUK protein 1 (Carma 1)|CARD11|CARMA1
Host
Rabbit
UniProt ID
Q9BXL7
Gene ID
84433
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
133 kDa
Background
Involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IK