Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
ARHGEF5
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
Rho guanine nucleotide exchange factor(GEF) 5
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Rho guanine nucleotide exchange factor 5|Ephexin-3|Guanine nucleotide regulatory protein TIM|Oncogene TIM|Transforming immortalized mammary oncogene|p60 TIM|ARHGEF5|TIM
Host
Rabbit
UniProt ID
Q12774
Gene ID
7984
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
60 kDa
Background
Guanine nucleotide exchange factor which activates Rho GTPases(PubMed:15601624). Strongly activates RHOA(PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1(By similarity). Involve