Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB, IP
Target
ARHGEF1
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
Rho guanine nucleotide exchange factor(GEF) 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Rho guanine nucleotide exchange factor 1|115 kDa guanine nucleotide exchange factor (p115-RhoGEF, p115RhoGEF)|Sub1.5|ARHGEF1
Host
Rabbit
UniProt ID
Q92888
Gene ID
9138
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
102-110 kDa
Background
Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. A