Storage ConditionsLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping ConditionsThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Molecular Weight20.9 KDa
Minimum PurityGreater than 95% as determined by reducing SDS-PAGE.
Other NameNEDD8
Neddylin
Neural precursor cell expressed developmentally down-regulated protein 8
Ubiquitin-like protein Nedd8
BackgroundHuman NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex,