Información del producto
Recombinant 2019-nCoV Papain-Like Protease
Información adicional
Size
50ug
Storage Conditions
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping Conditions
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
Upon receipt, store it immediately at the temperature listed below.
Molecular Weight
35.8 KDa
Minimum Purity
Greater than 95% as determined by reducing SDS-PAGE.
Other Name
PL-PRO
PLpro
Papain-like Protease
Replicase polyprotein 1a
pp1a
PLpro
Papain-like Protease
Replicase polyprotein 1a
pp1a
Background
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These pr
specifically, PLPro cleaves a site at the amino-terminus of the viral replicase region. In addition to its role in viral protein maturation, PLPro possesses a deubiquitinating and deISGylating activity. In vivo, this protease antagonizes innate immunity
specifically, PLPro cleaves a site at the amino-terminus of the viral replicase region. In addition to its role in viral protein maturation, PLPro possesses a deubiquitinating and deISGylating activity. In vivo, this protease antagonizes innate immunity