Storage ConditionsPBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
ApplicationsFC
TargetMouse IL-10
Formliquid
Recomended DilutionEach lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should ti
BackgroundIL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, T
and promotes mast cell proliferation in combination with IL-4.
inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis
stimulates Th2 cell response (which results in elevated antibody production)
suppresses the delayed type hypersensitivity response