Storage ConditionsPBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
ApplicationsFC
TargetHuman CD195
Formliquid
Recomended DilutionVolume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Plea
Type ClonalityMonoclonal
SynonymsCCR5
CategoryFlow cytometry Antibodies
HostMouse
UniProt IDP51681
Gene ID1234
Iso typeIgG2a, κ
ReactivityHuman
ConjugationFineTest®700
BackgroundCD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell d
modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.