Storage ConditionsPBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
ApplicationsFC
TargetMouse IL-10
Formliquid
Recomended DilutionVolume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Plea
BackgroundIL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IIL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IIL-10 inhibits IFN-γ,
and promotes mast cell proliferation in combination with IL-4.
inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis
stimulates Th2 cell response (which results in elevated antibody production)
suppresses the delayed type hypersensitivity response