Información del producto
PDGFRB antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
PDGFRB
Research Area
Signal Transduction, Metabolism, Cancer, Immunology, Developmental biology
Form
liquid
Recomended Dilution
IHC: 1:50-1:200
WB: 1:200-1:2000
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
platelet-derived growth factor receptor, beta polypeptide
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Platelet-derived growth factor receptor beta (PDGF-R-beta, PDGFR-beta)|Beta platelet-derived growth factor receptor|Beta-type platelet-derived growth factor receptor|CD140 antigen-like family member B|Platelet-derived growth factor receptor 1 (PDGFR-1)|PD
Host
Rabbit
UniProt ID
P09619
Gene ID
5159
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
50 kDa, 160-180 kDa
Background
Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiatio
the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PLCG1, PIK3R1, PTPN11, RASA1/GAP, CBL, SHC1 and NCK1. Activation of PLCG1 leads to the production of the cel
the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PLCG1, PIK3R1, PTPN11, RASA1/GAP, CBL, SHC1 and NCK1. Activation of PLCG1 leads to the production of the cel