Información del producto
ZC3H12A antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
ZC3H12A
Research Area
Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:200-1:1000
IP: 1:200-1:1000
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
zinc finger CCCH-type containing 12A
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Endoribonuclease ZC3H12A|Monocyte chemotactic protein-induced protein 1 (MCP-induced protein 1, MCPIP-1)|Regnase-1 (Reg1)|Zinc finger CCCH domain-containing protein 12A|ZC3H12A|MCPIP|MCPIP1
Host
Rabbit
UniProt ID
Q5D1E8
Gene ID
80149
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
66 kDa
Background
(Microbial infection) Exhibits broad antiviral activity by cleaving viral RNAs(PubMed:23355615). Binds to Japanese encephalitis virus(JEV) and dengue virus(DEN) RNAs(PubMed:23355615). Exhibits antiviral activity against HIV-1 in lymphocytes by decreasing
Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angiogenesis. Functions as an endoribon
promotes IL4-induced polarization of macrophages M1 into anti-inflammatory M2 state(By similarity). May also act as a transcription factor that regulates the expression of multiple genes involved in inflammatory response, angiogenesis, adipogenesis and ap
Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angiogenesis. Functions as an endoribon
promotes IL4-induced polarization of macrophages M1 into anti-inflammatory M2 state(By similarity). May also act as a transcription factor that regulates the expression of multiple genes involved in inflammatory response, angiogenesis, adipogenesis and ap