Información del producto
TRIM27 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP, IF
Target
TRIM27
Research Area
Cancer, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:20-1:200
IP: 1:500-1:5000
WB: 1:500-1:2000
IHC: 1:20-1:200
IP: 1:500-1:5000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
tripartite motif-containing 27
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Zinc finger protein RFP|RING finger protein 76|Ret finger protein|Tripartite motif-containing protein 27|TRIM27|RFP|RNF76
Host
Rabbit
UniProt ID
P14373
Gene ID
5987
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
58 kDa
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity
mediates the formation of 'Lys-48'-linked polyubiquitin chains
the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASH1, leading to promote endosomal F-actin assembly(PubMed:2345
mediates the formation of 'Lys-48'-linked polyubiquitin chains
the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASH1, leading to promote endosomal F-actin assembly(PubMed:2345