Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, IP, WB, IF
Target
TP53
Research Area
Cancer
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:50-1:500
IP: 1:500-1:2000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
tumor protein p53
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Cellular tumor antigen p53|Antigen NY-CO-13|Phosphoprotein p53|Tumor suppressor p53|TP53|P53
Host
Rabbit
UniProt ID
P04637
Gene ID
94241
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
53 kDa
Background
Acts as a tumor suppressor in many tumor types
induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. O
the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21(lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to ha