Información del producto
SSB antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
SSB
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:100 - 1:200
WB: 1:500 - 1:1000
WB: 1:500 - 1:1000
Type Clonality
polyclonal
Immunogen
Sjogren syndrome antigen B (autoantigen La)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Lupus La protein|La autoantigen|La ribonucleoprotein|Sjoegren syndrome type B antigen (SS-B)|SSB
Host
Rabbit
UniProt ID
P05455
Gene ID
6741
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
47 kDa
Background
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5&apos
and 3&apos
ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternat
and 3&apos
ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternat