Información del producto
SPOP antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
SPOP
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:50-1:500
IP : 1:500-1:1000
WB: 1:500-1:2000
IP : 1:500-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
speckle-type POZ protein
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Speckle-type POZ protein|HIB homolog 1|Roadkill homolog 1|SPOP
Host
Rabbit
UniProt ID
O43791
Gene ID
8405
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
42 kDa
Background
Component of a cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteaso
this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing hom
this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing hom