Información del producto
SF3B2 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
SF3B2
Research Area
Neuroscience, Epigenetics
Form
liquid
Recomended Dilution
IF: 1:50 - 1:200
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
splicing factor 3b, subunit 2, 145kDa
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Splicing factor 3B subunit 2|Pre-mRNA-splicing factor SF3b 145 kDa subunit (SF3b145)|Spliceosome-associated protein 145 (SAP 145)|SF3B2|SAP145
Host
Rabbit
UniProt ID
Q13435
Gene ID
10992
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
140 kDa
Background
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-m
s branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Sub
s branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Sub