Información del producto
RNF20 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IP
Target
RNF20
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
IP: 1:200-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
ring finger protein 20
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase BRE1A (BRE1-A, hBRE1)|RING finger protein 20|RING-type E3 ubiquitin transferase BRE1A|RNF20|BRE1A
Host
Rabbit
UniProt ID
Q5VTR2
Gene ID
56254
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
114 kDa
Background
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B(H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-
reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates th
reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates th