Información del producto
RIPK3 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IP, WB,IHC
Target
RIPK3
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
IHC: 1:100-1:400
IP: 1:200-1:1000
WB: 1:200-1:1000
IP: 1:200-1:1000
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
receptor-interacting serine-threonine kinase 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Receptor-interacting serine/threonine-protein kinase 3|RIP-like protein kinase 3|Receptor-interacting protein 3 (RIP-3)|RIPK3|RIP3
Host
Rabbit
UniProt ID
Q9Y572
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
57 kDa
Background
Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and