Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP
Target
RGS14
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
IP: 1:200-1:2000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
regulator of G-protein signaling 14
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Regulator of G-protein signaling 14 (RGS14)|RGS14
Host
Rabbit
UniProt ID
O43566
Gene ID
10636
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
60-65 kDa
Background
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G prot
a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division.