Información del producto
RBBP6 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
RBBP6
Research Area
Epigenetics, Immunology, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
retinoblastoma binding protein 6
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase RBBP6|Proliferation potential-related protein|Protein P2P-R|RING-type E3 ubiquitin transferase RBBP6|Retinoblastoma-binding Q protein 1 (RBQ-1)|Retinoblastoma-binding protein 6|p53-associated cellular protein of testis|RBBP6|P2
Host
Rabbit
UniProt ID
Q7Z6E9
Gene ID
5930
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
200 kDa
Background
E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome(PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-med
may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth(By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites(CFSs) in a ZBTB38-and MCM10-dependent manner. Controls ZBTB38 protein
may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth(By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites(CFSs) in a ZBTB38-and MCM10-dependent manner. Controls ZBTB38 protein