Información del producto
PTPRJ antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
PTPRJ
Research Area
Neuroscience, Immunology, Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
protein tyrosine phosphatase, receptor type, J
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta, R-PTP-eta)|Density-enhanced phosphatase 1 (DEP-1)|HPTP eta|Protein-tyrosine phosphatase receptor type J (R-PTP-J)|PTPRJ|DEP1
Host
Rabbit
UniProt ID
Q12913
Gene ID
5795
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
146-170 kDa
Background
Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET(variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation
through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor(TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, whil
through KDR dephosphorylation. Negative regulator of EGFR signaling pathway
through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation
through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor(TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, whil
through KDR dephosphorylation. Negative regulator of EGFR signaling pathway
through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation