Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB, IP, IF
Target
PICK1
Research Area
Neuroscience, Signal Transduction
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
protein interacting with PRKCA 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
PRKCA-binding protein|Protein interacting with C kinase 1|Protein kinase C-alpha-binding protein|PICK1|PRKCABP
Host
Rabbit
UniProt ID
Q9NRD5
Gene ID
9463
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
50-55 kDa
Background
Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization
the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor(AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses