Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
MZB1
Research Area
Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
hypothetical protein MGC29506
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Marginal zone B- and B1-cell-specific protein|Mesenteric estrogen-dependent adipose 7 (MEDA-7)|Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein, pERp1)|Proapoptotic caspase adapter protein|MZB1|MEDA7|PACA
Host
Rabbit
UniProt ID
Q8WU39
Gene ID
51237
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
21 kDa
Background
Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
Associates with immunoglobulin M(IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity(By similarity). Iso