Información del producto
MYL2 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB
Target
MYL2
Research Area
Neuroscience, Immunology, Cardiovascular
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
WB: 1:500-1:2000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
myosin, light chain 2, regulatory, cardiac, slow
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2, MLC-2v)|Cardiac myosin light chain 2|Myosin light chain 2, slow skeletal/ventricular muscle isoform (MLC-2s/v)|Ventricular myosin light chain 2|MYL2|MLC2
Host
Rabbit
UniProt ID
P10916
Gene ID
4633
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
18-20 kDa
Background
Contractile protein that plays a role in heart development and function(By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin h
as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin bi
as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin bi