Información del producto
MRTFA antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
MRTFA
Research Area
Stem Cells, Cardiovascular, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:20-1:200
WB: 1:500-1:2000
IHC: 1:20-1:200
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
megakaryoblastic leukemia(translocation) 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Myocardin-related transcription factor A (MRTF-A)|MKL/myocardin-like protein 1|Megakaryoblastic leukemia 1 protein|Megakaryocytic acute leukemia protein|MRTFA|KIAA1438|MAL|MKL1
Host
Rabbit
UniProt ID
Q969V6
Gene ID
57591
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
145 kDa
Background
Transcriptional coactivator of serum response factor(SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases
its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation(By similarity).
its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation(By similarity).