Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
MAP2K6
Research Area
Immunology, Metabolism
Form
liquid
Recomended Dilution
IF: 1:50 - 1:100
IHC: 1:50 - 1:500
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
mitogen-activated protein kinase kinase 6
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6, MAPKK 6)|MAPK/ERK kinase 6 (MEK 6)|Stress-activated protein kinase kinase 3 (SAPK kinase 3, SAPKK-3, SAPKK3)|MAP2K6|MEK6|MKK6|PRKMK6|SKK3
Host
Rabbit
UniProt ID
P52564
Gene ID
5608
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
37 kDa
Background
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MA
and for IFNG-dependent gene transcription. Has a role in osteoclast differentiation through NF-kappa-B transactivation by TNFSF11, and in endochondral ossification and since SOX9 is another likely downstream target of the p38 MAPK pathway. MAP2K6/MKK6 med