Información del producto
LGR4 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC
Target
LGR4
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
Type Clonality
polyclonal
Immunogen
leucine-rich repeat-containing G protein-coupled receptor 4
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Leucine-rich repeat-containing G-protein coupled receptor 4|G-protein coupled receptor 48|LGR4|GPR48
Host
Rabbit
UniProt ID
Q9BXB1
Gene ID
55366
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Background
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are
required for maintaining the ureteric bud in an undifferentiated state. Involved in the development of the anterior segment of the eye. Required during erythropoiesis. Also acts as a negative regulator of innate immunity by inhibiting TLR2/TLR4 associated
required for maintaining the ureteric bud in an undifferentiated state. Involved in the development of the anterior segment of the eye. Required during erythropoiesis. Also acts as a negative regulator of innate immunity by inhibiting TLR2/TLR4 associated