Información del producto
HP antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
HP
Research Area
Cardiovascular, Stem Cells, Metabolism, Signal Transduction, Cancer
Form
liquid
Recomended Dilution
WB: 1:2000 - 1:20000
Type Clonality
monoclonal
Immunogen
haptoglobin
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Haptoglobin|Zonulin|Haptoglobin alpha chain|Haptoglobin beta chain|HP
Host
Mouse
UniProt ID
P00738
Gene ID
3240
Purification
Protein A+G purification
Clone Number
7C8
Iso type
IgG2a
Reactivity
Human, Pig
Observed MW
42 kDa
Background
Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cell
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also a
Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also a
Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.