Información del producto
GABBR1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
GABBR1
Research Area
Neuroscience, Immunology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
gamma-aminobutyric acid(GABA) B receptor, 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1)|GABBR1|GPRC3A
Host
Rabbit
UniProt ID
Q9UBS5
Gene ID
2550
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
95 kDa
Background
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation c
Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.
Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.