Información del producto
FEN1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF, IP
Target
FEN1
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
IF: 1:10 - 1:100
IHC: 1:50 - 1:200
IP : 1:50 - 1:200
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IP : 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
flap structure-specific endonuclease 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Flap endonuclease 1 (FEN-1)|DNase IV|Flap structure-specific endonuclease 1|Maturation factor 1 (MF1, hFEN-1)|FEN1|RAD2
Host
Rabbit
UniProt ID
P39748
Gene ID
2237
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
42 kDa
Background
The protein encoded by this gene removes 5&apos
end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.
ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the subs
overhanging flaps in DNA repair and processes the 5&apos
end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.
ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the subs
overhanging flaps in DNA repair and processes the 5&apos