Información del producto
DYNLT1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
DYNLT1
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
IP: 1:200-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
dynein, light chain, Tctex-type 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Dynein light chain Tctex-type 1|Protein CW-1|T-complex testis-specific protein 1 homolog|DYNLT1|TCTEL1|TCTEX-1|TCTEX1
Host
Rabbit
UniProt ID
P63172
Gene ID
6993
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
12 kDa
Background
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the i
Plays a role in neuronal morphogenesis
inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation(By similarity).
the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis
the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a
Plays a role in neuronal morphogenesis
inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation(By similarity).
the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis
the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a