Información del producto
DAB2 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF, FC, IP
Target
DAB2
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:50-1:200
IP: 1:500-1:2000
WB: 1:500-1:5000
IHC: 1:50-1:200
IP: 1:500-1:2000
WB: 1:500-1:5000
Type Clonality
polyclonal
Immunogen
disabled homolog 2, mitogen-responsive phosphoprotein(Drosophila)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Disabled homolog 2|Adaptor molecule disabled-2|Differentially expressed in ovarian carcinoma 2 (DOC-2)|Differentially-expressed protein 2|DAB2|DOC2
Host
Rabbit
UniProt ID
P98082
Gene ID
1601
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
96 kDa
Background
Adapter protein that functions as clathrin-associated sorting protein(CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate(PtdIns(4,
seems to compete with AR for interaction with SRC. Plays a role in the CSF-1 signal transduction pathway. Plays a role in cellular differentiation. Involved in cell positioning and formation of visceral endoderm(VE) during embryogenesis and proposed to be
this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domain-containing proteins such as EPS15, EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis transmembrane conductance regulato
seems to compete with AR for interaction with SRC. Plays a role in the CSF-1 signal transduction pathway. Plays a role in cellular differentiation. Involved in cell positioning and formation of visceral endoderm(VE) during embryogenesis and proposed to be
this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domain-containing proteins such as EPS15, EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis transmembrane conductance regulato