Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IHC, IP
Target
CUX1
Research Area
Neuroscience, Cardiovascular, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IF: 1:10-1:100
IHC: 1:50-1:200
IP:1:500-1:2000
WB: 1:1000-1:3000
Type Clonality
polyclonal
Immunogen
cut-like homeobox 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Homeobox protein cut-like 1|CCAAT displacement protein (CDP)|CDP/Cux p200|Homeobox protein cux-1|CDP/Cux p110|CUX1|CUTL1
Host
Rabbit
UniProt ID
P39880
Gene ID
1523
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
80 kDa
Background
Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor
binds to the matrix attachment regions(MARs)(5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor(TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to t
may require the basic helix-loop-helix protein TCF4 as a coactivator(By similarity).