Información del producto
CUL1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
CUL1
Research Area
Cancer, Cell Division and Proliferation, Metabolism
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
IP: 1:200-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
cullin 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Cullin-1 (CUL-1)|CUL1
Host
Rabbit
UniProt ID
Q13616
Gene ID
8454
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
90 kDa
Background
Core component of multiple cullin-RING-based SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, se
the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(CCNF) directs ubiquitination of CCP110. SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2. SCF(FBXO9) directs ubiquiti
the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(CCNF) directs ubiquitination of CCP110. SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2. SCF(FBXO9) directs ubiquiti