Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB
Target
CREM
Research Area
Neuroscience, Signal Transduction, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
cAMP responsive element modulator
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
cAMP-responsive element modulator|Inducible cAMP early repressor (ICER)|CREM
Host
Rabbit
UniProt ID
Q03060
Gene ID
1390
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
36 kDa
Background
Isoform 6: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.
Transcriptional regulator that binds the cAMP response element(CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid matura