Información del producto
Collagen Type IV antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
Collagen Type IV
Research Area
Cancer, Immunology
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
WB: 1:200-1:2000
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
collagen, type IV, alpha 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Collagen alpha-2(IV) chain|Canstatin|COL4A2
Host
Rabbit
UniProt ID
P08572
Gene ID
1284
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
200 kDa
Background
Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and in
Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.