Información del producto
CNOT3 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IP
Target
CNOT3
Research Area
Cardiovascular, Metabolism
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
IP: 1:200-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
CCR4-NOT transcription complex, subunit 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
CCR4-NOT transcription complex subunit 3|CCR4-associated factor 3|Leukocyte receptor cluster member 2|CNOT3|KIAA0691|LENG2|NOT3
Host
Rabbit
UniProt ID
O75175
Gene ID
4849
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
120 kDa
Background
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and gen
may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress t
the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem(ES) cell identity.
may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress t
the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem(ES) cell identity.