Información del producto
CEBPB antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
CEBPB
Research Area
Epigenetics, Cardiovascular, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
CCAAT/enhancer binding protein(C/EBP), beta
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
CCAAT/enhancer-binding protein beta (C/EBP beta)|Liver activator protein (LAP)|Liver-enriched inhibitory protein (LIP)|Nuclear factor NF-IL6|Transcription factor 5 (TCF-5)|CEBPB|TCF5
Host
Rabbit
UniProt ID
P17676
Gene ID
1051
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Rat
Observed MW
36 kDa
Background
Important transcription factor regulating the expression of genes involved in immune and inflammatory responses(PubMed:1741402, PubMed:9374525, PubMed:12048245, PubMed:18647749). Plays also a significant role in adipogenesis, as well as in the gluconeogen
Isoform 2: Essential for gene expression induction in activated macrophages. Plays a major role in immune responses such as CD4(+) T-cell response, granuloma formation and endotoxin shock. Not essential for intracellular bacteria killing.
Isoform 3: Acts as a dominant negative through heterodimerization with isoform 2(PubMed:11741938). Promotes osteoblast differentiation and osteoclastogenesis(By similarity).
Isoform 2: Essential for gene expression induction in activated macrophages. Plays a major role in immune responses such as CD4(+) T-cell response, granuloma formation and endotoxin shock. Not essential for intracellular bacteria killing.
Isoform 3: Acts as a dominant negative through heterodimerization with isoform 2(PubMed:11741938). Promotes osteoblast differentiation and osteoclastogenesis(By similarity).